SCHEMBL28025360

SCHEMBL28025360

COc1c(C)c(C)cc2c1Cc1cc(C)c(C)cc1-2

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.32
CHEK1 O14757 1/20 0.31
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18261187 0.79 HTT (0.32)
SCHEMBL3819867 0.75 HPGD (0.33)
Hydrochloric Acid SCHEMBL28112707 0.73
Hydrochloric Acid SCHEMBL3274889 0.73
SCHEMBL11805772 0.72 MEN1 (0.36) ALDH1A1
SCHEMBL10917281 0.71 HTT (0.39) KDM4EALDH1A1GAA
SCHEMBL29633536 0.71 HTT (0.39) KDM4EALDH1A1GAA
SCHEMBL29633540 0.70 SLC22A8 (0.33)
SCHEMBL3274895 0.70
SCHEMBL29633480 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106543310-A A kind of olefin polymerization catalyst system and its application 中国石油化工股份有限公司 2017-03-29 CN claimed
CN-110498871-A A kind of alkoxyl magnesium carrier granular and its application SHANGHAI RES INSTITUTE OF CHEMICAL INDUSTRY CO LTD 2019-11-26 CN disclosed
CN-106543310-B A kind of olefin polymerization catalyst system and its application 中国石油化工股份有限公司 2019-06-28 CN disclosed
CN-106459539-B Polymer composition based on propylene 巴塞尔聚烯烃意大利有限公司 2018-05-11 CN disclosed
CN-107873036-A Prepolymerized catalyst component for polymerizing olefins 巴塞尔聚烯烃意大利有限公司 2018-04-03 CN disclosed
CN-105143528-B Polypropylene fibre 巴塞尔聚烯烃意大利有限公司 2018-02-13 CN disclosed
CN-105408112-B Heat-sealable polyolefins film and sheet material 巴塞尔聚烯烃意大利有限公司 2018-01-19 CN disclosed
CN-107043491-A Process for preparing impact resistant propylene polymer compositions 巴塞尔聚烯烃意大利有限责任公司 2017-08-15 CN disclosed
CN-106543310-A A kind of olefin polymerization catalyst system and its application 中国石油化工股份有限公司 2017-03-29 CN disclosed
CN-106459539-A Propylene-based polymer composition 巴塞尔聚烯烃意大利有限公司 2017-02-22 CN disclosed
CN-105899554-A Process for the preparation of propylene terpolymers and terpolymers obtained thereby 巴塞尔聚烯烃意大利有限公司 2016-08-24 CN disclosed
CN-105636994-A Process for the preparation of porous propylene polymers BASELL POLIOLEFINE ITALIA SRL 2016-06-01 CN disclosed
CN-105408112-A Heat-sealable polyolefin films and sheets BASELL POLIOLEFINE ITALIA SPA 2016-03-16 CN disclosed
CN-105143528-A Polypropylene fiber BASELL POLIOLEFINE SPA 2015-12-09 CN disclosed
CN-104837619-A Propylene-based terpolymers BASELL POLIOLEFINE SPA 2015-08-12 CN disclosed