SCHEMBL28025933

SCHEMBL28025933

Cc1cccc2c1C(c1ccccc1)=C[CH]2

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FABP4 P15090 1/20 0.35
CD44 P16070 1/20 0.34
MYC P01106 1/20 0.34
TSHR P16473 3/20 0.33
ACHE P22303 2/20 0.33
SRC P12931 1/20 0.33
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
ALDH1A1 P00352 2/20 0.32
LMNA P02545 1/20 0.32
ALOX12 P18054 1/20 0.32
FGFR1 P11362 1/20 0.32
FGFR2 P21802 1/20 0.32
FGFR4 P22455 1/20 0.32
FGFR3 P22607 1/20 0.32
RET P07949 1/20 0.32
RPA1 P27694 1/20 0.32
MCL1 Q07820 1/20 0.32
MEN1 O00255 2/20 0.31
RAB9A P51151 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27503901 0.78 PSMB5 (0.36) SRCALDH1A1LMNAMEN1KMT2A
SCHEMBL28025941 0.74 BRD4 (0.32) TSHRALDH1A1RAB9AKMT2ACYP3A4
SCHEMBL28907130 0.74 MYC (0.39) CD44MYCTSHRACHEALDH1A1
SCHEMBL28303645 0.73 BRD4 (0.31) TSHRALDH1A1RAB9AKMT2ACYP3A4
SCHEMBL27504259 0.73 PSMB5 (0.33) ALDH1A1LMNAMEN1KMT2ASMN1; SMN2
SCHEMBL5082785 0.73 CYP2A6 (0.36) CD44MYCTSHRACHESRC
SCHEMBL4426820 0.71 TSHR (0.50) FABP4CD44MYCTSHRACHE
SCHEMBL30396794 0.69 TSHR (0.47) FABP4MYCTSHRACHEMAOA
SCHEMBL28743155 0.69 PDCD1 (0.39) MAOBALDH1A1LMNAFGFR1HTR7
SCHEMBL28025451 0.69 ESR2 (0.36) TSHRMAOBALDH1A1LMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108137729-B Catalysts for forming multimodal polymers 埃克森美孚化学专利公司 2021-02-05 CN disclosed
CN-104822697-A Bridged metallocene compounds, catalyst systems and polymerization processes using the same EXXONMOBIL CHEM PATENTS INC 2015-08-05 CN disclosed