SCHEMBL28026707

SCHEMBL28026707

CCCCc1cccc(C(=O)O)c1OC(=O)CC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.47
MEN1 O00255 1/20 0.47
RECQL P46063 1/20 0.47
KMT2A Q03164 1/20 0.47
PPARA Q07869 3/20 0.45
PPARG P37231 2/20 0.45
BID P55957 6/20 0.43
MCL1 Q07820 6/20 0.43
BCL2L1 Q07817 5/20 0.43
BAK1 Q16611 5/20 0.43
KAT8 Q9H7Z6 2/20 0.43
SAE1 Q9UBE0 2/20 0.43
EP300 Q09472 1/20 0.43
KAT2A Q92830 1/20 0.43
KAT2B Q92831 1/20 0.43
KAT5 Q92993 1/20 0.43
HSD17B10 Q99714 2/20 0.41
MAPK1 P28482 1/20 0.41
ALDH1A1 P00352 1/20 0.41
HPGD P15428 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18685991 0.87 KDM4E (0.56) KDM4EMEN1RECQLKMT2APPARA
SCHEMBL28026662 0.85 TSHR (0.47) KDM4EMEN1KMT2AHSD17B10MAPK1
SCHEMBL1987893 0.84 PPARA (0.54) KDM4EMEN1RECQLKMT2APPARA
SCHEMBL22588786 0.82 PPARA (0.46) KDM4EMEN1RECQLKMT2APPARA
SCHEMBL975210 0.82 PTPN11 (0.46) PPARAPPARGBIDMCL1BCL2L1
SCHEMBL15547523 0.82 PPARA (0.47) KDM4EMEN1RECQLKMT2APPARA
SCHEMBL974446 0.81 PTPN11 (0.45) PPARAPPARGBIDMCL1BCL2L1
SCHEMBL28793611 0.81 PTPN11 (0.45) PPARAPPARGBIDMCL1BCL2L1
SCHEMBL975211 0.81 PTPN11 (0.45) PPARAPPARGBIDMCL1BCL2L1
SCHEMBL976080 0.81 PTPN11 (0.45) PPARAPPARGBIDMCL1BCL2L1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104829757-A Salicylate-compound-containing solid catalyst component for olefin polymerization, and preparation method and application thereof CHINESE ACAD INST CHEMISTRY 2015-08-12 CN disclosed