Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28026853 | 1.00 | KMT2A (0.55) | KMT2AALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL10692448 | 0.87 | POLB (0.59) | KMT2AALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL10693205 | 0.83 | KLK7 (0.53) | KMT2ARAB9ASMN1; SMN2NPC1TAAR1 | |
| SCHEMBL10693452 | 0.82 | SMN1; SMN2 (0.57) | KMT2ARAB9ASMN1; SMN2NPC1TAAR1 | |
| SCHEMBL6919966 | 0.82 | CNR1 (0.72) | KMT2AALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL29407117 | 0.81 | SMN1; SMN2 (0.60) | KMT2AALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL1405355 | 0.81 | SMN1; SMN2 (0.60) | KMT2AALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL1405358 | 0.81 | SMN1; SMN2 (0.60) | KMT2AALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL16609505 | 0.80 | SMN1; SMN2 (0.59) | KMT2AALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL27448741 | 0.80 | SMN1; SMN2 (0.59) | KMT2AALDH1A1RAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104744292-A | Preparation method of -2- ((4-nitrophenylethyl) amino) -2-oxo-1-phenylethyl acetate or derivative thereof | NANJING UNIVERSITY OF TECHNOLOGY | 2015-07-01 | — | — | CN | disclosed |