SCHEMBL28027045

SCHEMBL28027045

CCCC1CCC(CCc2ccc(C#Cc3ccc(CCC4CCC(CCC)CC4)cc3)cc2)CC1

nearest known ligand 0.48

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MAOB P27338 8/20 0.48
MAOA P21397 2/20 0.48
ACACB O00763 7/20 0.42
GPR84 Q9NQS5 1/20 0.39
HRH3 Q9Y5N1 1/20 0.38
FFAR1 O14842 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7510173 0.97 MAOB (0.52) MAOBMAOAACACBGPR84HRH3
SCHEMBL8036196 0.97 MAOB (0.52) MAOBMAOAACACBGPR84HRH3
SCHEMBL7510157 0.95 MAOB (0.44) MAOBMAOAACACBGPR84HRH3
SCHEMBL8050050 0.95 MAOB (0.44) MAOBMAOAACACBGPR84HRH3
SCHEMBL9512407 0.94 MAOB (0.50) MAOBMAOAACACBGPR84FFAR1
SCHEMBL9332669 0.94 MAOB (0.43) MAOBMAOAACACBGPR84HRH3
SCHEMBL8452789 0.94 MAOB (0.43) MAOBMAOAACACBHRH3FFAR1
SCHEMBL7914105 0.94 MAOB (0.43) MAOBMAOAACACBHRH3FFAR1
SCHEMBL9511383 0.92 HSD17B10 (0.45) MAOBMAOAHRH3
SCHEMBL9333534 0.92 MAOB (0.43) MAOBMAOAACACBGPR84HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103805208-B Dicyclohexyl ethylene group substituted diphenylamine alkynes liquid crystalline cpd and preparation method thereof SHAANXI NORMAL UNIVERSITY (CN) 2015-08-19 CN disclosed
CN-103805208-A Dicyclohexyl ethylene group substituted diphenylacetylene liquid crystal compound and preparation method thereof UNIV SHAANXI NORMAL 2014-05-21 CN disclosed