SCHEMBL28028092

Cc1cc2c(c(C)c1-c1cccc(COc3ccc4c(c3)OC[C@H]4CC(=O)O)c1)C(=O)C(COC(=O)C(C)(CC(C)(C)C)N(C)[SiH3])(COC(=O)C(C)(CC(C)(C)C)N(C)[SiH3])O2

nearest known ligand 0.57

Predicted protein targets (top 6)

	gene	UniProt	supporting neighbours	confidence
▸	FFAR1	O14842	20/20	0.57

▸	GNA15	P30679	1/20	0.51

▸	SLC10A1	Q14973	1/20	0.51

▸	ABCC2	Q92887	1/20	0.51

▸	SLCO1B3	Q9NPD5	1/20	0.51

▸	SLCO1B1	Q9Y6L6	1/20	0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL28027553	0.90	FFAR1 (0.43)	FFAR1
SCHEMBL28027992	0.86	FFAR1 (0.68)	FFAR1GNA15SLC10A1ABCC2SLCO1B3
SCHEMBL28027998	0.86	FFAR1 (0.68)	FFAR1GNA15SLC10A1ABCC2SLCO1B3
SCHEMBL28027385	0.84	FFAR1 (0.70)	FFAR1GNA15SLC10A1ABCC2SLCO1B3
SCHEMBL28028089	0.84	FFAR1 (0.57)	FFAR1GNA15SLC10A1ABCC2SLCO1B3
SCHEMBL28122533	0.81	FFAR1 (0.71)	FFAR1GNA15SLC10A1ABCC2SLCO1B3
SCHEMBL28027375	0.76	FFAR1 (0.77)	FFAR1GNA15SLC10A1ABCC2SLCO1B3
SCHEMBL28122551	0.76	FFAR1 (0.74)	FFAR1GNA15SLC10A1ABCC2SLCO1B3
SCHEMBL28027405	0.76	FFAR1 (0.74)	FFAR1GNA15SLC10A1ABCC2SLCO1B3
SCHEMBL16249163	0.74	FFAR1 (0.89)	FFAR1GNA15SLC10A1ABCC2SLCO1B3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-104870429-A	Benzofuran derivative, preparation method therefor, and medical application thereof	SICHUAN HAISCO PHARMACEUTICAL CO LTD	2015-08-26	—	—	CN	disclosed