Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 6/20 | 0.49 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | PNMT | P11086 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3766553 | 0.84 | MAPT (0.46) | MAPTMAOBLOXL2PNMTCYP3A4 | |
| SCHEMBL10347560 | 0.81 | MAPT (0.56) | MAPTMAOBLOXL2CYP3A4CYP2A6 | |
| SCHEMBL30663731 | 0.81 | MAPT (0.56) | MAPTMAOBLOXL2CYP3A4CYP2A6 | |
| SCHEMBL31542585 | 0.81 | MAPT (0.58) | MAPTMAOBLOXL2CYP3A4CYP2A6 | |
| SCHEMBL12578542 | 0.81 | ALOX5AP (0.40) | MAPTPNMTMEN1KMT2AHPGD | |
| SCHEMBL29172146 | 0.81 | MAPT (0.63) | MAPTMAOBLOXL2CYP3A4CYP2A6 | |
| SCHEMBL5808039 | 0.81 | MAPT (0.58) | MAPTMAOBLOXL2CYP3A4CYP2A6 | |
| SCHEMBL10821207 | 0.81 | MAPT (0.39) | MAPTPNMTCYP3A4HPGDSMN1; SMN2 | |
| SCHEMBL28689962 | 0.80 | MAPT (0.67) | MAPTMAOBCYP3A4CYP2A6MAOA | |
| Hydrochloric Acid SCHEMBL21694039 | 0.79 | MAPT (0.55) | MAPTMAOBLOXL2CYP3A4CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109384681-A | A kind of method of synthetic hydrochloric acid mexiletine | 南京理工大学 | 2019-02-26 | — | — | CN | claimed |
| CN-104973999-A | Novel method for preparing allene by cesium hydroxide catalysis | UNIV HUNAN | 2015-10-14 | — | — | CN | claimed |
| CN-104973999-A | Novel method for preparing allene by cesium hydroxide catalysis | UNIV HUNAN | 2015-10-14 | — | — | CN | disclosed |