Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 10/20 | 0.60 |
| ▸ | PLAU | P00749 | 1/20 | 0.59 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.59 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.58 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.55 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17393254 | 0.85 | KDM4E (0.62) | CHEK2PKN1PKN2HDAC6KMT2A | |
| SCHEMBL17393252 | 0.85 | KDM4E (0.62) | CHEK2PKN1PKN2HDAC6KMT2A | |
| SCHEMBL13167140 | 0.84 | HDAC6 (0.57) | CHEK2CYP3A4HDAC1HDAC2HDAC6 | |
| SCHEMBL17393379 | 0.82 | CHEK2 (0.56) | CHEK2CYP3A4MEN1KMT2A | |
| SCHEMBL1842124 | 0.82 | CHEK2 (0.61) | CHEK2MEN1KMT2A | |
| SCHEMBL17393611 | 0.82 | CHEK2 (0.56) | CHEK2CYP3A4MEN1KMT2A | |
| SCHEMBL10029167 | 0.82 | CHEK2 (0.60) | CHEK2PLAUPRSS1NR4A2 | |
| SCHEMBL10029168 | 0.82 | CHEK2 (0.61) | CHEK2MEN1KMT2A | |
| SCHEMBL1841112 | 0.82 | CHEK2 (0.60) | CHEK2PLAUPRSS1NR4A2 | |
| SCHEMBL17393277 | 0.82 | CHEK2 (0.57) | CHEK2PLAUPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104962543-B | A kind of oriented immobilization method of Bacillus subtilis neutral protease | 上海理工大学 | 2017-11-03 | — | — | CN | disclosed |
| CN-104962543-A | Oriented immobilization method for bacillus subtilis neutral protease | UNIV SHANGHAI SCIENCE & TECH | 2015-10-07 | — | — | CN | disclosed |