Pentachlorophenol

Pentachlorophenol

SCHEMBL28030118

CCl.Oc1c(Cl)c(Cl)c(Cl)c(Cl)c1Cl.Oc1c(Cl)c(Cl)c(Cl)c(Cl)c1Cl

nearest known ligand 0.83

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 8/20 0.83
TSHR P16473 7/20 0.83
HPGD P15428 7/20 0.83
ALDH1A1 P00352 3/20 0.83
MEN1 O00255 2/20 0.83
LMNA P02545 2/20 0.83
MAPT P10636 2/20 0.83
KMT2A Q03164 2/20 0.83
CYP3A4 P08684 6/20 0.48
CYP1A2 P05177 4/20 0.48
CYP2C9 P11712 4/20 0.48
HIF1A Q16665 3/20 0.48
CYP2C19 P33261 1/20 0.48
MAPK1 P28482 3/20 0.46
CASP1 P29466 1/20 0.44
ALOX15 P16050 2/20 0.38
USP2 O75604 1/20 0.38
TP53 P04637 1/20 0.38
GLA P06280 1/20 0.38
THRB P10828 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pentachlorophenol SCHEMBL23121452 0.91 HSD17B10 (1.00) HSD17B10TSHRHPGDALDH1A1MEN1
Pentachlorophenol SCHEMBL5315995 0.91 HSD17B10 (1.00) HSD17B10TSHRHPGDALDH1A1MEN1
Perchlorobenzene SCHEMBL28269084 0.91 HSD17B10 (1.00) HSD17B10TSHRHPGDALDH1A1MEN1
Pentachlorophenol SCHEMBL1330735 0.91 HSD17B10 (1.00) HSD17B10TSHRHPGDALDH1A1MEN1
Pentachlorophenol SCHEMBL1492 0.91 HSD17B10 (1.00) HSD17B10TSHRHPGDALDH1A1MEN1
Pentachlorophenol SCHEMBL27653302 0.88 TSHR (0.77) HSD17B10TSHRHPGDALDH1A1MEN1
Pentachlorophenol SCHEMBL3751225 0.87 HSD17B10 (0.91) HSD17B10TSHRHPGDALDH1A1MEN1
Pentachlorophenol SCHEMBL11459279 0.87 HSD17B10 (0.91) HSD17B10TSHRHPGDALDH1A1MEN1
Pentachlorophenol SCHEMBL21647360 0.87 HSD17B10 (0.91) HSD17B10TSHRHPGDALDH1A1MEN1
Pentachlorophenol SCHEMBL22027593 0.87 HSD17B10 (0.91) HSD17B10TSHRHPGDALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105017240-A Pesticidal compositions DOW AGROSCIENCES LLC 2015-11-04 CN disclosed