Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | GRM6 | O15303 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aniline SCHEMBL28297518 | 0.86 | TSHR (0.75) | TSHRGRM6LMNACYP3A4CYP1A2 | |
| SCHEMBL102574 | 0.86 | TSHR (0.65) | TSHRCYP1A2CYP2C19KDM4EALDH1A1 | |
| SCHEMBL29941499 | 0.86 | TSHR (0.65) | TSHRCYP1A2CYP2C19KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL20840273 | 0.84 | TSHR (0.62) | TSHRCYP1A2CYP2C19KDM4EALDH1A1 | |
| Aniline SCHEMBL27667982 | 0.80 | TSHR (0.58) | TSHRLMNACYP3A4CYP1A2CYP2C9 | |
| Aniline SCHEMBL28030200 | 0.79 | CYP1A2 (0.47) | TSHRGRM6LMNACYP3A4CYP1A2 | |
| SCHEMBL819145 | 0.75 | TSHR (0.59) | TSHRKDM4EALDH1A1MAPTNISCH | |
| SCHEMBL1379434 | 0.74 | CYP3A4 (0.56) | TSHRGRM6LMNACYP3A4CYP1A2 | |
| SCHEMBL1379432 | 0.74 | TSHR (0.60) | TSHRLMNACYP3A4CYP1A2CYP2C9 | |
| Trifluoroacetic Acid SCHEMBL15393051 | 0.74 | TSHR (0.46) | TSHRLMNAKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104927072-A | Solvent-resistant polyimide thin film with low thermal expansion coefficient and preparation method for polyimide thin film | LU AN CITY DUERBANG INSULATION MATERIALS CO LTD | 2015-09-23 | — | — | CN | disclosed |