Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3695399 | 1.00 | POLB (0.39) | POLBKMT2AEPHX1HPGDALDH1A1 | |
| SCHEMBL3695403 | 1.00 | POLB (0.39) | POLBKMT2AEPHX1HPGDALDH1A1 | |
| SCHEMBL228161 | 0.82 | ATM (0.40) | POLBKMT2AEPHX1HPGDALDH1A1 | |
| SCHEMBL11162057 | 0.82 | POLB (0.38) | POLBKMT2AEPHX1HPGDALDH1A1 | |
| SCHEMBL28029704 | 0.82 | POLB (0.38) | POLBKMT2AEPHX1HPGDALDH1A1 | |
| SCHEMBL228162 | 0.82 | ATM (0.40) | POLBKMT2AEPHX1HPGDALDH1A1 | |
| SCHEMBL20476202 | 0.82 | EPHX1 (0.31) | KMT2AEPHX1HPGD | |
| SCHEMBL23440760 | 0.81 | POLB (0.37) | POLBKMT2AEPHX1HPGDALDH1A1 | |
| SCHEMBL3689106 | 0.81 | POLB (0.37) | POLBKMT2AEPHX1HPGDALDH1A1 | |
| SCHEMBL3689110 | 0.81 | POLB (0.37) | POLBKMT2AEPHX1HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104854103-A | Acylaminocycloalkyl compounds suitable for treating disorders that respond to modulation of dopamine d3 receptor | ABBVIE DEUTSCHLAND | 2015-08-19 | — | — | CN | disclosed |