Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 3/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | AXL | P30530 | 1/20 | 0.47 |
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | TYR | P14679 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30720998 | 0.87 | NPC1 (0.50) | CACNA1HPTGS1PTGS2AXLCYP19A1 | |
| SCHEMBL30721031 | 0.77 | NPC1 (0.71) | CACNA1HPTGS1PTGS2AXLPLK1 | |
| SCHEMBL28033401 | 0.73 | ABCG2 (0.65) | CYP19A1ABCG2ADORA3CYP3A4 | |
| SCHEMBL9067953 | 0.72 | AXL (0.84) | AXLCYP19A1ARADORA3HSD11B1 | |
| SCHEMBL9067956 | 0.72 | AXL (0.84) | AXLCYP19A1ARADORA3HSD11B1 | |
| SCHEMBL29368881 | 0.70 | CYP19A1 (0.54) | PTGS2CYP19A1ABCG2CYP3A4NPC1 | |
| SCHEMBL29650043 | 0.69 | CYP19A1 (0.78) | PTGS1PTGS2CYP19A1TYRPOLB | |
| SCHEMBL20450286 | 0.68 | NPC1 (0.69) | PTGS1PTGS2AXLPLK1CYP19A1 | |
| SCHEMBL28035035 | 0.66 | CYP19A1 (0.78) | PTGS1PTGS2CYP19A1TYRPOLB | |
| SCHEMBL22465747 | 0.66 | CACNA1H (0.77) | CACNA1HPTGS2PLK1ARADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105030759-A | Novel application of 5,2',3'-trihydroxy-6,7-methylenedioxy-flavanone compound | UNIV BEIJING NORMAL | 2015-11-11 | — | — | CN | disclosed |
| CN-105030759-A | Novel application of 5,2',3'-trihydroxy-6,7-methylenedioxy-flavanone compound | UNIV BEIJING NORMAL | 2015-11-11 | — | — | CN | disclosed |