Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.75 |
| ▸ | LMNA | P02545 | 3/20 | 0.75 |
| ▸ | HPGD | P15428 | 2/20 | 0.75 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | HTT | P42858 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | TNKS | O95271 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.50 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.50 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12325324 | 0.84 | KDM4E (0.66) | KDM4ELMNAHPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL11398949 | 0.81 | KDM4E (0.62) | KDM4ELMNAHPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL11388357 | 0.80 | KDM4E (0.60) | KDM4ELMNAHPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL5613922 | 0.80 | HPGD (0.53) | KDM4ELMNAHPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL11388353 | 0.79 | KDM4E (0.63) | KDM4ELMNAHPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL11856459 | 0.79 | KDM4E (0.59) | KDM4ELMNAHPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL11865739 | 0.78 | KDM4E (0.77) | KDM4ELMNAHPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL11856467 | 0.78 | KDM4E (0.58) | KDM4ELMNAHPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL29463595 | 0.75 | MAPT (0.68) | KDM4ELMNASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL3397825 | 0.75 | MAPT (0.68) | KDM4ELMNASMN1; SMN2HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105753965-A | Conjugate Based Systems For Controlled Drug Delivery | 斯马特塞尔斯公司 | 2016-07-13 | — | — | CN | disclosed |
| CN-104936595-A | Methods and compositions for locally increasing body fat | TOPOKINE THERAPEUTICS INC | 2015-09-23 | — | — | CN | disclosed |