Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.63 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.56 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.56 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | FAAH | O00519 | 2/20 | 0.52 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28869329 | 0.85 | MAPT (1.00) | MAPTSMN1; SMN2BLMKMT2ATAS1R3 | |
| SCHEMBL20236800 | 0.84 | MAPT (0.80) | MAPTSMN1; SMN2BLMKMT2ATAS1R3 | |
| SCHEMBL15955932 | 0.82 | MAPT (0.76) | MAPTSMN1; SMN2BLMKMT2ATAS1R3 | |
| SCHEMBL3949148 | 0.79 | MAPT (0.88) | MAPTSMN1; SMN2BLMKMT2ATAS1R3 | |
| SCHEMBL20236897 | 0.79 | MAPT (0.88) | MAPTSMN1; SMN2BLMKMT2ATAS1R3 | |
| SCHEMBL3949152 | 0.79 | MAPT (0.88) | MAPTSMN1; SMN2BLMKMT2ATAS1R3 | |
| SCHEMBL8361624 | 0.79 | SMN1; SMN2 (0.97) | MAPTSMN1; SMN2BLMKMT2ATAS1R3 | |
| SCHEMBL4559572 | 0.79 | SMN1; SMN2 (0.91) | MAPTSMN1; SMN2BLMKMT2ATAS1R3 | |
| SCHEMBL5195426 | 0.78 | SMN1; SMN2 (1.00) | MAPTSMN1; SMN2BLMKMT2ATAS1R3 | |
| SCHEMBL13234920 | 0.77 | MAPT (0.87) | MAPTSMN1; SMN2BLMKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104945470-A | Tripeptide epoxy ketone compound constructed by heterocycle as well as preparation method and application thereof | UNIV ZHEJIANG | 2015-09-30 | — | — | CN | disclosed |