Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 2/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.45 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL28032936 | 0.87 | MAPT (0.63) | POLBMAPTLMNASMN1; SMN2CA12 | |
| SCHEMBL654537 | 0.85 | POLB (0.69) | POLBALOX5MAPTLMNAKDM4E | |
| Tert-Butyl Formate SCHEMBL28033001 | 0.78 | FLT3 (0.49) | NPC1RAB9AKMT2A | |
| Tert-Butyl Formate SCHEMBL28827129 | 0.77 | POLB (0.46) | POLBSMN1; SMN2CA12CA2CA9 | |
| SCHEMBL30965820 | 0.76 | POLB (0.63) | POLBCNR2CNR1CA12CA2 | |
| Tert-Butyl Formate SCHEMBL27990929 | 0.76 | TDP1 (0.39) | POLBSMN1; SMN2CA12CA2CA9 | |
| SCHEMBL20236629 | 0.76 | MEN1 (0.68) | POLBALOX5CNR2CNR1MAPT | |
| SCHEMBL27979652 | 0.75 | CA12 (0.71) | ALOX5CNR2CNR1MAPTLMNA | |
| Tert-Butyl Formate SCHEMBL27722072 | 0.74 | TDP1 (0.43) | POLBCA12CA2CA9TDP1 | |
| SCHEMBL12995570 | 0.74 | POLB (0.69) | POLBMAPTSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104945470-A | Tripeptide epoxy ketone compound constructed by heterocycle as well as preparation method and application thereof | UNIV ZHEJIANG | 2015-09-30 | — | — | CN | disclosed |