Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.56 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | EP300 | Q09472 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Phenylthiazole SCHEMBL28033487 | 0.87 | PDPK1 (0.75) | PDPK1LOXL2ADRB2CYP2A6HDAC3 | |
| SCHEMBL468046 | 0.85 | PDPK1 (0.63) | PDPK1LOXL2ADRB2CYP2A6HSD11B1 | |
| SCHEMBL28033488 | 0.84 | PDPK1 (0.56) | PDPK1LOXL2TLR7ADRB2CYP2A6 | |
| Acetic Acid SCHEMBL9382210 | 0.78 | PDPK1 (0.55) | PDPK1LOXL2ADRB2HDAC3HDAC4 | |
| SCHEMBL16159714 | 0.76 | PDPK1 (0.68) | PDPK1LOXL2ADRB2CYP2A6HDAC3 | |
| SCHEMBL16159836 | 0.76 | PDPK1 (0.68) | PDPK1LOXL2ADRB2CYP2A6HDAC3 | |
| SCHEMBL28487238 | 0.76 | PDPK1 (0.52) | PDPK1LOXL2ADRB2CYP2A6HSD11B1 | |
| SCHEMBL722198 | 0.75 | PDPK1 (0.77) | PDPK1LOXL2ADRB2CYP2A6HDAC3 | |
| SCHEMBL16159074 | 0.75 | PDPK1 (0.66) | PDPK1LOXL2ADRB2CYP2A6HDAC3 | |
| SCHEMBL16159066 | 0.75 | PDPK1 (0.66) | PDPK1LOXL2ADRB2CYP2A6HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104892640-A | 2-phenyl-6-benzoyl-thiazolo[3,2-b][1,2,4]-triazole derivative and application thereof | UNIV SHIJIAZHUANG | 2015-09-09 | — | — | CN | claimed |
| CN-104892640-A | 2-phenyl-6-benzoyl-thiazolo[3,2-b][1,2,4]-triazole derivative and application thereof | UNIV SHIJIAZHUANG | 2015-09-09 | — | — | CN | disclosed |