Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | CRHBP | P24387 | 2/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9484533 | 0.84 | KCNH2 (0.62) | KCNH2MAPT | |
| SCHEMBL1260665 | 0.82 | KCNH2 (0.66) | KCNH2MAPTSIGMAR1 | |
| SCHEMBL1262236 | 0.82 | KCNH2 (0.66) | KCNH2MAPTSIGMAR1 | |
| SCHEMBL9485273 | 0.82 | KCNH2 (0.66) | KCNH2MAPTSIGMAR1 | |
| SCHEMBL3453399 | 0.82 | KCNH2 (0.66) | KCNH2MAPTSIGMAR1 | |
| SCHEMBL11359571 | 0.82 | KCNH2 (0.66) | KCNH2MAPTSIGMAR1 | |
| SCHEMBL7606887 | 0.82 | KCNH2 (0.66) | KCNH2MAPTSIGMAR1 | |
| SCHEMBL1260761 | 0.82 | KCNH2 (0.66) | KCNH2MAPTSIGMAR1 | |
| SCHEMBL9005868 | 0.82 | KCNH2 (0.66) | KCNH2MAPTSIGMAR1 | |
| SCHEMBL9005882 | 0.82 | KCNH2 (0.66) | KCNH2MAPTSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104926755-A | Nitrobenzene di-acyl benzylamine AMPK (adenosine monophosphate activated protein kinase) activator, method for manufacturing same and application of nitrobenzene di-acyl benzylamine AMPK activator | FOSHAN SAIWEISI MEDICINE SCIENCE & TECHNOLOGY CO LTD | 2015-09-23 | — | — | CN | disclosed |
| CN-104926755-A | Nitrobenzene di-acyl benzylamine AMPK (adenosine monophosphate activated protein kinase) activator, method for manufacturing same and application of nitrobenzene di-acyl benzylamine AMPK activator | FOSHAN SAIWEISI MEDICINE SCIENCE & TECHNOLOGY CO LTD | 2015-09-23 | — | — | CN | disclosed |