Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.60 |
| ▸ | FLT3 | P36888 | 1/20 | 0.54 |
| ▸ | GSK3B | P49841 | 1/20 | 0.54 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ESRRA | P11474 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | STS | P08842 | 1/20 | 0.45 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.44 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27983551 | 0.89 | NOTUM (0.61) | NOTUMFLT3GSK3BUSP30NPC1 | |
| SCHEMBL616473 | 0.88 | NOTUM (0.60) | NOTUMFLT3GSK3BUSP30KEAP1 | |
| SCHEMBL28033861 | 0.85 | NOTUM (0.57) | NOTUMKEAP1NPC1RAB9AESRRA | |
| SCHEMBL23153549 | 0.83 | ESRRA (0.59) | NOTUMNPC1ESRRA | |
| SCHEMBL21338835 | 0.82 | NOTUM (0.55) | NOTUMFLT3GSK3BUSP30KEAP1 | |
| SCHEMBL28033305 | 0.82 | CA1 (0.57) | NOTUMFLT3GSK3BNPC1RAB9A | |
| SCHEMBL17444789 | 0.80 | NOTUM (0.56) | NOTUMFLT3GSK3BUSP30NPC1 | |
| SCHEMBL14692525 | 0.79 | POLB (0.59) | NOTUMUSP30ESRRA | |
| SCHEMBL30403029 | 0.79 | NOTUM (0.54) | NOTUMFLT3GSK3BUSP30NPC1 | |
| SCHEMBL17444785 | 0.78 | USP30 (0.57) | NOTUMFLT3GSK3BUSP30NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104926738-A | Application of 1,2,3-triazole-4-hydrazide derivatives to preparation of agricultural bactericide | UNIV NANJING AGRICULTURAL | 2015-09-23 | — | — | CN | disclosed |