Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | ACACA | Q13085 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 2/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | MMP12 | P39900 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | TNKS | O95271 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | PRKCI | P41743 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10288701 | 0.75 | BRD4 (0.44) | BRD4APPPIK3C3ACACBKCNH2 | |
| SCHEMBL24721331 | 0.72 | BRD4 (0.42) | BRD4APPPIK3C3ACACBKCNH2 | |
| SCHEMBL586478 | 0.72 | BRD4 (0.51) | BRD4APPPIK3C3SYKMMP12 | |
| SCHEMBL12896064 | 0.71 | BRD4 (0.41) | BRD4APPPIK3C3ACACBKCNH2 | |
| SCHEMBL15058223 | 0.70 | AHR (0.47) | BRD4APPPIK3C3KDM4EALDH1A1 | |
| SCHEMBL20364680 | 0.69 | PIK3C3 (0.44) | BRD4APPPIK3C3ACACBKCNH2 | |
| SCHEMBL925859 | 0.68 | PRKCI (0.52) | BRD4APPPIK3C3TNKSKDM4E | |
| SCHEMBL418946 | 0.68 | BRD4 (0.44) | BRD4APPPIK3C3SYKALOX5AP | |
| SCHEMBL1269027 | 0.68 | TYR (0.45) | BRD4APPPIK3C3KDM4EALDH1A1 | |
| SCHEMBL15058364 | 0.68 | AHR (0.45) | BRD4APPPIK3C3SYKALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102939282-B | Compounds for the treatment of diseases related to amyloid or amyloid-like proteins | AC IMMUNE S.A. (CH) | 2015-12-02 | — | — | CN | disclosed |