Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 19/20 | 0.59 |
| ▸ | PDE4A | P27815 | 7/20 | 0.59 |
| ▸ | PDE4C | Q08493 | 7/20 | 0.59 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28033773 | 0.94 | PDE4B (0.55) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL4278555 | 0.94 | PDE4B (0.63) | PDE4BPDE4APDE4CPDE4DMAPT | |
| SCHEMBL2090601 | 0.94 | PDE4B (0.60) | PDE4BPDE4APDE4CPDE4DMAPT | |
| SCHEMBL28033787 | 0.90 | PDE4B (0.57) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL23047404 | 0.89 | PDE4B (0.56) | PDE4BPDE4APDE4CPDE4DMAPT | |
| SCHEMBL2803310 | 0.89 | PDE4B (0.55) | PDE4BPDE4APDE4CPDE4DMAPT | |
| SCHEMBL17050365 | 0.88 | NOTUM (0.50) | PDE4BPDE4APDE4CPDE4DMAPT | |
| SCHEMBL15650723 | 0.88 | CA12 (0.53) | PDE4BPDE4APDE4CPDE4DMAPT | |
| SCHEMBL29790148 | 0.88 | NOTUM (0.50) | PDE4BPDE4APDE4CPDE4DMAPT | |
| SCHEMBL30362197 | 0.88 | CA12 (0.53) | PDE4BPDE4APDE4CPDE4DMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105085429-A | Heteroaromatic derivative and application thereof to medicament | GUANGDONG HEC PHARMACEUTICAL | 2015-11-25 | — | — | CN | disclosed |