Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 19/20 | 0.89 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16363042 | 0.94 | PARP1 (1.00) | PARP1 | |
| SCHEMBL5621808 | 0.91 | PARP1 (0.72) | PARP1 | |
| SCHEMBL5621907 | 0.86 | PARP1 (0.66) | PARP1 | |
| SCHEMBL16364065 | 0.84 | PARP1 (1.00) | PARP1 | |
| SCHEMBL16363558 | 0.84 | PARP1 (1.00) | PARP1 | |
| SCHEMBL16363554 | 0.83 | PARP1 (1.00) | PARP1 | |
| SCHEMBL16363044 | 0.81 | PARP1 (1.00) | PARP1 | |
| SCHEMBL16364066 | 0.81 | PARP1 (1.00) | PARP1 | |
| SCHEMBL5620745 | 0.80 | PARP1 (0.74) | PARP1 | |
| SCHEMBL20449682 | 0.80 | PARP1 (0.56) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104981468-A | Benzimidazole-2-piperazine heterocyclic compound, pharmaceutical composition thereof, preparation method and use thereof | SHANGHAI HUILUN LIFE SCIENCE & TECHNOLOGY CO LTD | 2015-10-14 | — | — | CN | disclosed |