Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | MYLK | Q15746 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 5/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9739896 | 0.74 | BCHE (0.44) | BCHEACHEALDH1A1LMNAGFER | |
| SCHEMBL11073006 | 0.73 | BCHE (0.41) | BCHEACHEHDAC6ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL28771874 | 0.72 | BCHE (0.42) | BCHEACHEALDH1A1LMNAGFER | |
| SCHEMBL28308135 | 0.71 | ESR1 (0.34) | MYLKESR1ESR2HDAC6ALDH1A1 | |
| SCHEMBL7291421 | 0.65 | CYP2C19 (0.41) | ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL3386305 | 0.65 | BCHE (0.41) | BCHEACHEALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL28115415 | 0.65 | KDM4E (0.42) | BCHEACHEHDAC6ALDH1A1GFER | |
| SCHEMBL4983323 | 0.64 | POLB (0.33) | BCHEACHEALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL28131846 | 0.63 | NOX1 (0.42) | BCHEACHELMNASMN1; SMN2 | |
| SCHEMBL17394655 | 0.63 | BCHE (0.39) | BCHEACHELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105085433-B | Substituted amide phenol compound and preparation method thereof, pharmaceutical composition and purposes | 中国科学院上海药物研究所 | 2019-06-25 | — | — | CN | disclosed |
| CN-105085433-A | Substituted-amide phenolic compound, preparation method, pharmaceutical composition and application thereof | SHANGHAI INST MATERIA MEDICA | 2015-11-25 | — | — | CN | disclosed |