Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 15/20 | 1.00 |
| ▸ | MEN1 | O00255 | 14/20 | 1.00 |
| ▸ | NPC1 | O15118 | 10/20 | 1.00 |
| ▸ | RAB9A | P51151 | 8/20 | 1.00 |
| ▸ | MAPT | P10636 | 3/20 | 1.00 |
| ▸ | HTT | P42858 | 2/20 | 1.00 |
| ▸ | POLB | P06746 | 1/20 | 1.00 |
| ▸ | MCL1 | Q07820 | 1/20 | 1.00 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.72 |
| ▸ | LMNA | P02545 | 2/20 | 0.72 |
| ▸ | GAA | P10253 | 1/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.72 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.67 |
| ▸ | ATM | Q13315 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | ECE2 | P0DPD6 | 1/20 | 0.55 |
| ▸ | LCK | P06239 | 1/20 | 0.54 |
| ▸ | CD74 | P04233 | 1/20 | 0.53 |
| ▸ | MIF | P14174 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28035483 | 1.00 | KMT2A (1.00) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL14681471 | 0.87 | KMT2A (0.77) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL28153886 | 0.85 | KMT2A (0.78) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL16971024 | 0.81 | KMT2A (1.00) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL16971022 | 0.81 | KMT2A (1.00) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL12282409 | 0.78 | MEN1 (1.00) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL14681376 | 0.76 | KMT2A (0.68) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL27940924 | 0.75 | MEN1 (0.68) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL12316856 | 0.75 | MEN1 (0.75) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL12281445 | 0.74 | LCK (0.67) | KMT2AMEN1NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105859757-A | 8-hydroxyquinoline terbium complex tetramer crystal as well as preparation method and application thereof | 广东工业大学 | 2016-08-17 | — | — | CN | disclosed |
| CN-105017295-A | Novel near-infrared luminescence 8-hydroxyquinoline-type rare earth ytterbium complex tetramer crystal and preparation method thereof | UNIV GUANGDONG TECHNOLOGY | 2015-11-04 | — | — | CN | disclosed |