Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 20/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17271364 | 0.84 | LRRK2 (1.00) | LRRK2 | |
| SCHEMBL15870206 | 0.83 | LRRK2 (1.00) | LRRK2 | |
| SCHEMBL15865096 | 0.83 | LRRK2 (1.00) | LRRK2 | |
| SCHEMBL15865136 | 0.81 | LRRK2 (1.00) | LRRK2 | |
| SCHEMBL15865391 | 0.81 | LRRK2 (1.00) | LRRK2 | |
| SCHEMBL15864659 | 0.79 | LRRK2 (1.00) | LRRK2 | |
| SCHEMBL15865278 | 0.77 | LRRK2 (0.89) | LRRK2 | |
| SCHEMBL15864930 | 0.76 | LRRK2 (1.00) | LRRK2 | |
| SCHEMBL15865025 | 0.76 | LRRK2 (1.00) | LRRK2 | |
| SCHEMBL15870145 | 0.76 | LRRK2 (1.00) | LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104903311-A | Aminopyridine derived compounds as LRRK2 inhibitors | LUNDBECK & CO AS H | 2015-09-09 | — | — | CN | claimed |
| CN-104903311-A | Aminopyridine derived compounds as LRRK2 inhibitors | LUNDBECK & CO AS H | 2015-09-09 | — | — | CN | disclosed |