SCHEMBL2803570

SCHEMBL2803570

[CH2]C[Si](C)(C)C(C)(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10795138 0.73
SCHEMBL7159317 0.71
SCHEMBL20189041 0.71
SCHEMBL15863920 0.69
SCHEMBL15066581 0.69
SCHEMBL6971086 0.67
SCHEMBL7134793 0.67
SCHEMBL5683569 0.67
SCHEMBL21879209 0.66
SCHEMBL9506612 0.65 NR1H2 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024140934-A1 PREPARATION METHOD FOR LINKER-DRUG CONJUGATE AND INTERMEDIATE THEREOF 上海复旦张江生物医药股份有限公司 2024-07-04 WO claimed
CN-116217654-A Preparation method of linker drug conjugate and intermediate thereof 上海复旦张江生物医药股份有限公司 2023-06-06 CN claimed
CN-116217655-A Preparation method of intermediate of linker drug conjugate 上海复旦张江生物医药股份有限公司 2023-06-06 CN claimed
CN-116178386-A Preparation method of linker drug conjugate and intermediate thereof 上海复旦张江生物医药股份有限公司 2023-05-30 CN claimed
US-20140360367-A1 ORGANOPOLYSILOXANES INCLUDING SILICON-BONDED TRIALKYLSILYL-SUBSTITUTED ORGANIC GROUPS DOW CORNING CORPORATION 2014-12-11 US claimed
CN-104169334-A Organopolysiloxanes including silicon-bonded trialkylsilyl-substituted organic groups DOW CORNING 2014-11-26 CN claimed
EP-2797987-A1 ORGANOPOLYSILOXANES INCLUDING SILICON-BONDED TRIALKYLSILYL-SUBSTITUTED ORGANIC GROUPS Dow Corning Corporation (US) 2014-11-05 EP claimed
WO-2013101938-A1 ORGANOPOLYSILOXANES INCLUDING SILICON-BONDED TRIALKYLSILYL-SUBSTITUTED ORGANIC GROUPS DOW CORNING CORPORATION (US) 2013-07-04 WO claimed
EP-0292806-B1 Substituted vinyl cephalosporins, process for their preparation and their use as medicines BAYER AG (DE) 1994-11-02 EP claimed
US-5324721-A 3-Substituted cephalosporins, and their use as medicaments BAYER AKTIENGESELLSCHAFT (DE) 1994-06-28 US claimed
EP-0292808-B1 Substituted vinyl cephalosporins, process for their preparation and their use as medicines BAYER AG (DE) 1994-03-02 EP claimed
EP-0477717-A2 New 3-substituted cephalosporins, process for their preparation and their use as medicinal preparations BAYER AG (DE) 1992-04-01 EP claimed
US-4980348-A HETEROANELLATED PHENYLGLYCINE-BETA-LACTAM ANTIBIOTICS BAYER AKTIENGESELLSCHAFT (DE) 1990-12-25 US claimed
US-4973685-A PENICILLINS AND CEPHALOSPORINS BAYER AKTIENGESELLSCHAFT (DE) 1990-11-27 US claimed
EP-0326887-A1 Beta-lactam antibiotics, process for their preparation and their use as and in therapeutic agents BAYER AG (DE) 1989-08-09 EP claimed
US-4841042-A Process for the preparation of carbapenem intermediates BAYER AKTIENGESELLSCHAFT (DE) 1989-06-20 US claimed
US-4840946-A Benzazolythio-carbapenem antibiotics BAYER AKTIENGESELLSCHAFT (DE) 1989-06-20 US claimed
CN-88103111-A Substituted cephalosporins, process for their preparation and their use as medicaments 1988-12-28 CN claimed
EP-0292808-A2 Substituted vinyl cephalosporins, process for their preparation and their use as medicines BAYER AG (DE) 1988-11-30 EP claimed
EP-0292806-A2 Substituted vinyl cephalosporins, process for their preparation and their use as medicines BAYER AG (DE) 1988-11-30 EP claimed