Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | PLK1 | P53350 | 6/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | DHFR | P00374 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.31 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.31 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.31 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.31 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28341398 | 0.87 | CCNE2 (0.38) | KMT2AALDH1A1MAPK1PLK1MAPT | |
| SCHEMBL27926249 | 0.78 | PTPN1 (0.34) | ALDH1A1MAPK1TDP1CNR2ERN1 | |
| SCHEMBL27770330 | 0.77 | CHRM1 (0.43) | TP53CNR2LMNA | |
| SCHEMBL27670405 | 0.76 | CNR2 (0.34) | CNR2 | |
| SCHEMBL27997552 | 0.76 | CREBBP (0.38) | ALDH1A1MAPK1TDP1KDM4ECNR2 | |
| SCHEMBL27951823 | 0.76 | CNR2 (0.41) | CNR2 | |
| SCHEMBL28054208 | 0.76 | CNR2 (0.34) | CNR2 | |
| SCHEMBL28826410 | 0.75 | CNR2 (0.43) | CNR2 | |
| SCHEMBL28818119 | 0.75 | KDM4E (0.34) | KMT2AALDH1A1MAPK1TDP1MAPT | |
| SCHEMBL27799440 | 0.75 | CNR2 (0.37) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105085508-A | Method for synthesizing rivaroxaban key intermediate | UNIV PEKING FOUNDER GROUP CO | 2015-11-25 | — | — | CN | disclosed |