Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | AURKB | Q96GD4 | 4/20 | 0.47 |
| ▸ | AURKA | O14965 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MC4R | P32245 | 1/20 | 0.46 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17135168 | 0.87 | AURKB (0.55) | MAPTSMN1; SMN2TP53ALDH1A1AURKB | |
| SCHEMBL17134819 | 0.79 | TP53 (0.51) | MAPTSMN1; SMN2TP53GAATHRB | |
| SCHEMBL17135080 | 0.79 | AURKB (0.62) | MAPTSMN1; SMN2TP53ALDH1A1AURKB | |
| SCHEMBL17135291 | 0.75 | MAPT (0.40) | MAPTSMN1; SMN2ALDH1A1MAPK1AURKB | |
| SCHEMBL17135156 | 0.74 | EGFR (0.50) | MAPTSMN1; SMN2HTTALDH1A1AURKB | |
| SCHEMBL4713013 | 0.73 | SYK (0.67) | MAPTSMN1; SMN2HTTALDH1A1MAPK1 | |
| SCHEMBL17134535 | 0.72 | AURKB (0.55) | MAPTSMN1; SMN2TP53ALDH1A1AURKB | |
| SCHEMBL17134589 | 0.71 | TP53 (0.51) | MAPTTP53GAAAURKBAURKA | |
| SCHEMBL23493854 | 0.70 | MAPT (0.77) | MAPTPOLBSMN1; SMN2TP53GAA | |
| SCHEMBL17134742 | 0.70 | AURKB (0.56) | MAPTSMN1; SMN2TP53ALDH1A1AURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104995173-A | Nitrogen-containing heterocyclic compound | KYOWA HAKKO KIRIN CO LTD | 2015-10-21 | — | — | CN | disclosed |