Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 4/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.46 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.46 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.42 |
| ▸ | HNF4A | P41235 | 1/20 | 0.42 |
| ▸ | BID | P55957 | 4/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.42 |
| ▸ | BAK1 | Q16611 | 3/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8949856 | 0.86 | FOLH1 (0.76) | FOLH1KMT2APTGER1PTGER4PTGER3 | |
| SCHEMBL5033866 | 0.86 | FOLH1 (0.66) | FOLH1KMT2APTGER1PTGER4PTGER3 | |
| SCHEMBL25171586 | 0.83 | FOLH1 (0.71) | FOLH1KMT2APTGER1PTGER4PTGER3 | |
| SCHEMBL4370868 | 0.83 | FOLH1 (1.00) | FOLH1KMT2APTGER1PTGER4PTGER3 | |
| SCHEMBL8872410 | 0.82 | FOLH1 (0.70) | FOLH1KMT2APTGER1PTGER4PTGER3 | |
| SCHEMBL4588820 | 0.82 | DPP4 (0.56) | FOLH1KMT2APTGER1PTGER4PTGER3 | |
| SCHEMBL27617768 | 0.81 | FOLH1 (0.49) | FOLH1KMT2A | |
| SCHEMBL25181448 | 0.81 | FOLH1 (0.68) | FOLH1KMT2APTGER1PTGER4PTGER3 | |
| SCHEMBL25264013 | 0.81 | FOLH1 (0.68) | FOLH1BIDMCL1BCL2L1BAK1 | |
| SCHEMBL25185377 | 0.80 | FOLH1 (0.66) | FOLH1BIDMCL1BCL2L1BAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105008347-A | Isoquinoline compounds as potassium ion channel inhibitors | BRISTOL MYERS SQUIBB CO | 2015-10-28 | — | — | CN | disclosed |