Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 15/20 | 0.53 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2576017 | 0.84 | BCHE (0.55) | BCHEKCNA3CES2 | |
| SCHEMBL27883387 | 0.83 | BCHE (0.53) | BCHEKCNA3CES2 | |
| SCHEMBL27810920 | 0.82 | BCHE (0.61) | BCHEKCNA3 | |
| SCHEMBL27652150 | 0.79 | HDAC3 (0.60) | BCHEKCNA3 | |
| SCHEMBL16369737 | 0.79 | TSHR (0.59) | BCHECES2 | |
| SCHEMBL27557534 | 0.79 | MC4R (0.59) | BCHECES2 | |
| SCHEMBL27742584 | 0.79 | F2 (0.63) | BCHEKCNA3 | |
| SCHEMBL27630590 | 0.78 | HDAC3 (0.62) | BCHEKCNA3 | |
| SCHEMBL27923505 | 0.78 | BCHE (0.57) | BCHECES2 | |
| SCHEMBL27709635 | 0.77 | BCHE (0.59) | BCHEKCNA3CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105008362-A | Pyrrolo [2,3-D ] pyrimidine derivatives as janus-related kinase (JAK) inhibitors | PFIZER | 2015-10-28 | — | — | CN | disclosed |