SCHEMBL28037076

SCHEMBL28037076

O=C=Nc1ccc(-c2ccsc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 4/20 0.47
CYP2B6 P20813 3/20 0.47
CYP2E1 P05181 2/20 0.47
CYP3A4 P08684 2/20 0.44
TSHR P16473 1/20 0.44
ERN1 O75460 4/20 0.41
KCNH2 Q12809 1/20 0.40
CYP17A1 P05093 1/20 0.40
CYP11B1 P15538 1/20 0.40
CYP11B2 P19099 1/20 0.40
ACMSD Q8TDX5 1/20 0.38
PTPRC P08575 1/20 0.38
LPL P06858 1/20 0.38
LIPG Q9Y5X9 1/20 0.38
CHEK2 O96017 1/20 0.37
GSK3B P49841 1/20 0.37
MAPK1 P28482 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
GRIA4 P48058 1/20 0.36
CYP2C9 P11712 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL241534 0.81 CYP3A4 (0.61) CYP3A4TSHRMAPK1TDP1
SCHEMBL23721668 0.81 CYP3A4 (0.61) CYP3A4TSHRMAPK1TDP1
Hydrogen Sulfide SCHEMBL3894665 0.79 CYP3A4 (0.58) CYP3A4TSHRMAPK1TDP1
Water SCHEMBL3898007 0.79 CYP3A4 (0.58) CYP3A4TSHRMAPK1TDP1
SCHEMBL424170 0.77
SCHEMBL27989815 0.76 CYP2A6 (0.74) CYP2A6CYP2B6CYP2E1CYP3A4ERN1
SCHEMBL2114610 0.74 CYP3A4 (0.54) CYP3A4TSHRMAPK1TDP1
SCHEMBL2548776 0.74 CYP2A6 (0.52) CYP2A6CYP2B6CYP2E1CYP3A4ERN1
SCHEMBL15430 0.73 CYP3A4 (0.70) CYP3A4TSHRMAPK1TDP1
SCHEMBL28122599 0.73 ERN1 (0.39) CYP2A6CYP2B6CYP2E1CYP3A4ERN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103080269-B Photochromic composition TOKUYAMA CORP. (JP) 2015-12-16 CN disclosed