SCHEMBL28037147

SCHEMBL28037147

O=CC(Cn1cncn1)c1ccc(Oc2ccc(Cl)cc2)cc1C(F)(F)F

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
AR P10275 1/20 0.40
KMT2A Q03164 3/20 0.35
KDM4E B2RXH2 2/20 0.35
ALDH1A1 P00352 2/20 0.35
TSHR P16473 1/20 0.34
HTT P42858 3/20 0.33
POLB P06746 2/20 0.33
HPGD P15428 1/20 0.33
MAPT P10636 1/20 0.33
MEN1 O00255 1/20 0.33
CYP3A4 P08684 1/20 0.33
LMNA P02545 1/20 0.33
CYP19A1 P11511 1/20 0.33
FAAH O00519 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27674389 0.86 KMT2A (0.41) KMT2AKDM4EALDH1A1TSHRHTT
SCHEMBL20526065 0.85 AR (0.41) ARKMT2AKDM4EALDH1A1TSHR
SCHEMBL20184136 0.85 AR (0.41) ARKMT2AKDM4EALDH1A1TSHR
SCHEMBL29678012 0.85 AR (0.41) ARKMT2AKDM4EALDH1A1TSHR
SCHEMBL28037146 0.85 AR (0.39) ARKMT2AKDM4EALDH1A1TSHR
SCHEMBL20267837 0.84 AR (0.40) ARKMT2AKDM4EALDH1A1TSHR
SCHEMBL30779648 0.84 AR (0.40) ARKMT2AKDM4EALDH1A1TSHR
SCHEMBL17769818 0.83 AR (0.41) ARKMT2AKDM4EALDH1A1TSHR
SCHEMBL20641133 0.82 AR (0.38) ARKMT2AKDM4EALDH1A1TSHR
SCHEMBL20875218 0.81 POLB (0.39) ARKMT2AKDM4EALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105050406-A Composition comprising triazole compound BASF SE 2015-11-11 CN disclosed