SCHEMBL28037634

SCHEMBL28037634

Oc1ccc(-c2nc3cc(O)ccc3nc2-c2ccccc2)cc1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.79
MEN1 O00255 3/20 0.79
ALDH1A1 P00352 5/20 0.58
KDM4E B2RXH2 4/20 0.58
L3MBTL1 Q9Y468 4/20 0.58
ATM Q13315 1/20 0.58
TLR9 Q9NR96 1/20 0.58
GAA P10253 2/20 0.57
HPGD P15428 2/20 0.57
NPC1 O15118 1/20 0.57
RAB9A P51151 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
MAPT P10636 2/20 0.54
PIK3CG P48736 1/20 0.54
TDP1 Q9NUW8 3/20 0.52
LMNA P02545 3/20 0.52
NTSR1 P30989 1/20 0.50
RAD51 Q06609 1/20 0.50
MMP3 P08254 1/20 0.50
BCL2L1 Q07817 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28037189 1.00 KMT2A (0.79) KMT2AMEN1ALDH1A1KDM4EL3MBTL1
SCHEMBL8112060 0.96 KMT2A (0.71) KMT2AMEN1ALDH1A1KDM4EL3MBTL1
SCHEMBL9891119 0.91 KMT2A (0.76) KMT2AMEN1ALDH1A1KDM4EL3MBTL1
SCHEMBL28044788 0.90 KMT2A (0.70) KMT2AMEN1ALDH1A1KDM4EL3MBTL1
SCHEMBL28044883 0.90 KMT2A (0.70) KMT2AMEN1ALDH1A1KDM4EL3MBTL1
SCHEMBL8407359 0.88 KMT2A (1.00) KMT2AMEN1ALDH1A1KDM4EL3MBTL1
SCHEMBL9692642 0.86 KMT2A (0.69) KMT2AMEN1ALDH1A1KDM4EL3MBTL1
SCHEMBL7155536 0.86 KMT2A (0.69) KMT2AMEN1ALDH1A1KDM4EL3MBTL1
SCHEMBL28041435 0.86 KMT2A (0.81) KMT2AMEN1ALDH1A1KDM4EL3MBTL1
SCHEMBL28041643 0.86 KMT2A (0.81) KMT2AMEN1ALDH1A1KDM4EL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105061466-B Main chain bisphenol type quinoxalinyl benzoxazine and preparation method thereof 哈尔滨工程大学 2017-06-20 CN claimed
CN-105061466-A Main chain bisphenol type quinoxaline benzoxazine and preparation method thereof UNIV HARBIN ENG 2015-11-18 CN claimed
CN-105061466-B Main chain bisphenol type quinoxalinyl benzoxazine and preparation method thereof 哈尔滨工程大学 2017-06-20 CN disclosed
CN-105061466-A Main chain bisphenol type quinoxaline benzoxazine and preparation method thereof UNIV HARBIN ENG 2015-11-18 CN disclosed