Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.53 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | SCN1A | P35498 | 1/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.44 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24991514 | 0.86 | TSHR (0.57) | TSHRTP53PDCD1CD274NPC1 | |
| SCHEMBL28716117 | 0.82 | TSHR (0.57) | TSHRTP53PDCD1CD274NPC1 | |
| Benzoic Acid 1-Methylethyl Ester SCHEMBL9343935 | 0.82 | PDCD1 (0.75) | TSHRTP53PDCD1CD274NPC1 | |
| SCHEMBL10767133 | 0.81 | TSHR (0.52) | TSHRTP53PDCD1CD274NPC1 | |
| SCHEMBL4951962 | 0.81 | TSHR (0.60) | TSHRTP53PDCD1CD274NPC1 | |
| SCHEMBL24614006 | 0.80 | TSHR (0.50) | TSHRTP53PDCD1CD274NPC1 | |
| Ammonia Solution, Strong SCHEMBL16468685 | 0.80 | TSHR (0.59) | TSHRTP53PDCD1CD274NPC1 | |
| SCHEMBL6660758 | 0.79 | TSHR (0.63) | TSHRTP53PDCD1CD274NPC1 | |
| SCHEMBL10239104 | 0.79 | TSHR (0.63) | TSHRTP53PDCD1CD274NPC1 | |
| Benzoic Acid 1-Methylethyl Ester SCHEMBL96918 | 0.79 | PDCD1 (0.78) | TSHRTP53PDCD1CD274NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105164161-A | Neuroactive steroids, compositions, and uses thereof | SAGE THERAPEUTICS INC | 2015-12-16 | — | — | CN | disclosed |