Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 2/20 | 0.67 |
| ▸ | GSK3B | P49841 | 1/20 | 0.67 |
| ▸ | BCHE | P06276 | 1/20 | 0.66 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.56 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | LDHA | P00338 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 3/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28147063 | 0.90 | FLT3 (0.63) | FLT3GSK3BBCHEABCB1ABCG2 | |
| SCHEMBL31158277 | 0.86 | FLT3 (0.58) | FLT3GSK3BBCHEABCB1ABCG2 | |
| SCHEMBL28653156 | 0.86 | BCHE (0.57) | FLT3GSK3BBCHEABCB1ABCG2 | |
| SCHEMBL28516007 | 0.85 | FLT3 (0.57) | FLT3GSK3BBCHEABCB1ABCG2 | |
| SCHEMBL28510543 | 0.84 | FLT3 (0.56) | FLT3GSK3BBCHEABCB1ABCG2 | |
| SCHEMBL28415505 | 0.84 | FLT3 (0.56) | FLT3GSK3BBCHEABCB1ABCG2 | |
| SCHEMBL28319778 | 0.83 | FLT3 (0.67) | FLT3GSK3BBCHEPTGS2KDR | |
| SCHEMBL28326485 | 0.82 | BCHE (0.54) | FLT3GSK3BBCHEABCB1ABCG2 | |
| SCHEMBL28309773 | 0.82 | BCHE (0.56) | FLT3GSK3BBCHEABCB1ABCG2 | |
| SCHEMBL16983157 | 0.82 | BCHE (0.60) | FLT3GSK3BBCHEABCB1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106588787-A | Arylformyl group-containing 1,2,3-triazole ligand, and preparation method and application thereof | 昆明理工大学 | 2017-04-26 | — | — | CN | claimed |
| CN-110396068-B | 4-o-alkoxy aryl-1, 2, 3-triazole derivative, and synthesis method and application thereof | 昆明理工大学 | 2023-01-20 | — | — | CN | disclosed |
| CN-110563659-B | Method for preparing 1,2, 3-triazole compound by heterogeneous copper catalysis in one pot | 浙江工业大学 | 2020-08-21 | — | — | CN | disclosed |
| CN-110563659-A | Method for preparing 1,2, 3-triazole compound by heterogeneous copper catalysis in one pot | 浙江工业大学 | 2019-12-13 | — | — | CN | disclosed |
| CN-106588787-B | A kind of application of the triazole of 1,2,3- containing sweet-smelling formacyl ligand | 昆明理工大学 | 2019-09-27 | — | — | CN | disclosed |
| CN-106588788-B | The method of one pot of two-step method synthesis 1,2,3- triazole compound | 河南师范大学 | 2019-07-16 | — | — | CN | disclosed |
| CN-104945341-B | A kind of method of the triazole compound of three components one pot process 1,2,3 | 河南师范大学 | 2018-03-02 | — | — | CN | disclosed |
| CN-106588787-A | Arylformyl group-containing 1,2,3-triazole ligand, and preparation method and application thereof | 昆明理工大学 | 2017-04-26 | — | — | CN | disclosed |
| CN-104945341-A | Method for synthesizing 1,2,3-triazole compound through three components in one pot | UNIV HENAN NORMAL | 2015-09-30 | — | — | CN | disclosed |