Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | CNR1 | P21554 | 3/20 | 0.42 |
| ▸ | CNR2 | P34972 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28038424 | 1.00 | SMN1; SMN2 (0.55) | SMN1; SMN2CNR1CNR2MEN1KMT2A | |
| SCHEMBL28038427 | 1.00 | SMN1; SMN2 (0.55) | SMN1; SMN2CNR1CNR2MEN1KMT2A | |
| SCHEMBL28038719 | 0.99 | SMN1; SMN2 (0.56) | SMN1; SMN2CNR1CNR2MEN1KMT2A | |
| SCHEMBL28038421 | 0.89 | SMN1; SMN2 (0.60) | SMN1; SMN2CNR1CNR2MEN1KMT2A | |
| SCHEMBL3579717 | 0.82 | SMN1; SMN2 (0.52) | SMN1; SMN2CNR1CNR2MEN1KMT2A | |
| SCHEMBL1527735 | 0.81 | SMN1; SMN2 (0.51) | SMN1; SMN2MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL28038420 | 0.80 | CNR1 (0.38) | SMN1; SMN2CNR1CNR2SMPD1 | |
| SCHEMBL28038715 | 0.80 | CNR1 (0.38) | SMN1; SMN2CNR1CNR2SMPD1 | |
| SCHEMBL28038756 | 0.80 | CNR1 (0.38) | SMN1; SMN2CNR1CNR2SMPD1 | |
| SCHEMBL6442004 | 0.79 | SMN1; SMN2 (0.78) | SMN1; SMN2MEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105037346-A | Pyrazol bi-amide compounds containing 1,2,3-thiadiazole and synthetic method and application thereof | UNIV CHINA AGRICULTURAL | 2015-11-11 | — | — | CN | disclosed |