Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL711996 | 0.95 | — | — | |
| Silver SCHEMBL16651975 | 0.92 | GSR (0.44) | GSRALDH1A1TDP1 | |
| Ammonia Solution, Strong SCHEMBL21352471 | 0.92 | GSR (0.44) | GSRALDH1A1TDP1 | |
| SCHEMBL25620921 | 0.81 | — | — | |
| SCHEMBL11579175 | 0.81 | — | — | |
| SCHEMBL220160 | 0.79 | GSR (0.39) | GSRALDH1A1 | |
| SCHEMBL462502 | 0.79 | GSR (0.39) | GSRALDH1A1 | |
| SCHEMBL221241 | 0.79 | GSR (0.39) | GSRALDH1A1 | |
| SCHEMBL28235963 | 0.79 | GSR (0.39) | GSR | |
| Water SCHEMBL23421028 | 0.78 | GSR (0.38) | GSRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104984351-A | Method for preparing nitroglycerin propylene glycol solution | MAYINGLONG PHARMACEUTICAL GROUP CO LTD | 2015-10-21 | — | — | CN | disclosed |
| CN-103525904-A | Method for detecting genetic types of mitochondria acetaldehyde dehydrogenase by utilizing high-resolution melting curve analysis technology | SHANGHAI CHINA BETTER LIFE MEDICAL HIGH TECH CO LTD | 2014-01-22 | — | — | CN | disclosed |
| CN-101349634-A | Detection method for evaluating curative effect to treat angina pectoris by grisounites series drug treatment | SHANGHAI ZHONGYOU MEDICINE HIG (CN) | 2009-01-21 | — | — | CN | disclosed |