Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | PLK2 | Q9NYY3 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29399907 | 1.00 | NPC1 (0.46) | NPC1RAB9AKMT2AMEN1ESR1 | |
| SCHEMBL30561220 | 0.87 | KMT2A (0.46) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL776632 | 0.86 | NPC1 (0.47) | NPC1RAB9AKMT2AMEN1ESR1 | |
| SCHEMBL5701094 | 0.86 | TSHR (0.45) | NPC1KMT2ALMNATSHR | |
| SCHEMBL28698767 | 0.85 | MAPT (0.47) | NPC1RAB9AKMT2AMEN1ESR1 | |
| SCHEMBL28117122 | 0.84 | TSHR (0.43) | NPC1KMT2ALMNATSHR | |
| SCHEMBL27650528 | 0.83 | NPC1 (0.49) | NPC1RAB9AKMT2AMEN1ESR1 | |
| SCHEMBL10500574 | 0.83 | NPC1 (0.45) | NPC1RAB9AKMT2AMEN1ESR1 | |
| Acetic Acid SCHEMBL8684459 | 0.82 | TSHR (0.44) | KMT2AESR1LMNATSHRHPGD | |
| SCHEMBL779011 | 0.81 | NPC1 (0.44) | NPC1RAB9AKMT2AMEN1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115444780-A | Personal care compositions with glutathione precursors comprising nicotinamide and amino acids | 联合利华知识产权控股有限公司 | 2022-12-09 | — | — | CN | disclosed |
| CN-110121332-B | Personal care compositions with glutathione precursors comprising nicotinamide and amino acids | 联合利华知识产权控股有限公司 | 2022-11-08 | — | — | CN | disclosed |
| CN-110325168-B | Personal care compositions containing cystine | 联合利华知识产权控股有限公司 | 2022-10-21 | — | — | CN | disclosed |
| CN-114767562-A | Topical skin lightening additives and compositions with amino acid and nicotinamide compounds | 联合利华知识产权控股有限公司 | 2022-07-22 | — | — | CN | disclosed |
| CN-110099672-B | Topical skin lightening additives and compositions with amino acid and nicotinamide compounds | 联合利华知识产权控股有限公司 | 2022-05-24 | — | — | CN | disclosed |
| CN-110121330-B | Personal care compositions with glutathione precursors comprising 4-substituted resorcinols and amino acids | 联合利华知识产权控股有限公司 | 2022-04-29 | — | — | CN | disclosed |
| CN-110121329-B | Topical skin lightening additives and compositions with amino acids and PPAR-activated fatty acids | 联合利华知识产权控股有限公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-107531655-B | N-aralkylcarbonyl-piperazine and N-aralkylcarbonyl-homopiperazine compounds and personal care compositions containing the same | 荷兰联合利华有限公司 | 2021-03-12 | — | — | CN | disclosed |
| CN-107548387-B | N-arylalkyl carbonyldiamine compounds and personal care compositions containing them | 荷兰联合利华有限公司 | 2020-08-25 | — | — | CN | disclosed |
| CN-103260594-B | Leave-on non-solid skin conditioning compositions comprising 12-hydroxystearic acid | UNILEVER NEDERLAND B.V. (NL) | 2015-11-25 | — | — | CN | disclosed |