Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.50 |
| ▸ | GSK3A | P49840 | 1/20 | 0.50 |
| ▸ | CDK9 | P50750 | 1/20 | 0.50 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.50 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.50 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.46 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 3/20 | 0.43 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | TYK2 | P29597 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 6/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4630887 | 0.83 | GSK3A (0.53) | HSP90AA1CDK5GSK3ACDK9TAOK1 | |
| Hydrochloric Acid SCHEMBL7857018 | 0.81 | GSK3A (0.51) | HSP90AA1CDK5GSK3ACDK9TAOK1 | |
| SCHEMBL28038743 | 0.81 | CDK5 (0.58) | HSP90AA1CDK5TAOK1CLK4CDK1 | |
| SCHEMBL16916919 | 0.74 | JAK2 (0.52) | CDK5GSK3ACDK9TAOK1CLK4 | |
| SCHEMBL16996884 | 0.74 | GSK3A (0.48) | CDK5GSK3ACDK9TAOK1CLK4 | |
| SCHEMBL29919700 | 0.74 | SCN9A (0.53) | CDK5CDK1CCNB1CCNA2CCNE1 | |
| SCHEMBL31247573 | 0.74 | KDM4E (0.57) | CDK5GSK3ACDK9CLK4CDK1 | |
| SCHEMBL28936140 | 0.74 | SCN9A (0.53) | CDK5CDK1CCNB1CCNA2CCNE1 | |
| SCHEMBL27606961 | 0.74 | GSK3A (0.48) | CDK5GSK3ACDK9TAOK1CLK4 | |
| SCHEMBL4666187 | 0.73 | RAD52 (0.59) | HSP90AA1KDRMKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105051030-A | Diaminoheteroaryl substituted indazoles | Bayer Pharma AG | 2015-11-11 | — | — | CN | claimed |
| CN-105051030-A | Diaminoheteroaryl substituted indazoles | Bayer Pharma AG | 2015-11-11 | — | — | CN | disclosed |