SCHEMBL28039384

SCHEMBL28039384

[CH2]C(CCCCC)(c1ccc2ccccc2c1)c1ccc2ccccc2c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.40
LMNA P02545 1/20 0.40
RAB9A P51151 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
CYP2A6 P11509 2/20 0.39
CYP1A2 P05177 1/20 0.39
CETP P11597 1/20 0.38
EPHX1 P07099 1/20 0.38
CNR2 P34972 3/20 0.37
CNR1 P21554 2/20 0.37
PTPN1 P18031 1/20 0.37
HDAC3 O15379 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC2 Q92769 1/20 0.36
BCHE P06276 1/20 0.35
HTT P42858 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
SLC6A2 P23975 1/20 0.35
SLC6A4 P31645 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28039372 0.98 CETP (0.40) NPC1LMNARAB9ASMN1; SMN2CYP2A6
SCHEMBL28039343 0.95 CYP2A6 (0.40) NPC1LMNARAB9ASMN1; SMN2CYP2A6
SCHEMBL28039349 0.82 NPC1 (0.39) NPC1LMNARAB9ASMN1; SMN2CYP2A6
SCHEMBL10688950 0.81 CNR2 (0.52) CNR2CNR1
SCHEMBL10685133 0.80 CNR2 (0.55) CNR2CNR1
SCHEMBL10583140 0.80 CNR2 (0.55) CNR2CNR1
SCHEMBL28039398 0.77 ESR1 (0.44) NPC1LMNARAB9ASMN1; SMN2CYP2A6
SCHEMBL11404984 0.75 CNR2 (0.53) CNR2CNR1
SCHEMBL28039080 0.75 ESR1 (0.46) NPC1LMNARAB9ASMN1; SMN2CYP2A6
SCHEMBL28039380 0.72 CYP2A6 (0.41) CYP2A6CYP1A2PTPN1CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104955332-A Method for controlling arthropod pest SUMITOMO CHEMICAL CO 2015-09-30 CN disclosed