Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | SYK | P43405 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 3/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | ABL1 | P00519 | 2/20 | 0.39 |
| ▸ | BCR | P11274 | 2/20 | 0.39 |
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
| ▸ | PRKACG | P22612 | 1/20 | 0.39 |
| ▸ | PRKACB | P22694 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4712352 | 0.85 | HTT (0.51) | HTTSYKMAPK1SRCABL1 | |
| SCHEMBL6617756 | 0.84 | HTT (0.54) | HTTSYKMAPK1SRCEGFR | |
| SCHEMBL24668609 | 0.84 | CDK1 (0.47) | HTTSYKMAPK1SRCEGFR | |
| SCHEMBL15992691 | 0.83 | HTT (0.51) | HTTSYKMAPK1EGFRBRD4 | |
| SCHEMBL30069455 | 0.82 | HTT (0.53) | HTTSYKMAPK1EGFRMAPT | |
| SCHEMBL28382393 | 0.82 | HTT (0.53) | HTTSYKMAPK1EGFRMAPT | |
| SCHEMBL30596936 | 0.81 | HTT (0.47) | HTTSYKMAPK1KMT2AKDM4E | |
| SCHEMBL26107898 | 0.81 | HTT (0.47) | HTTSYKMAPK1KMT2AKDM4E | |
| SCHEMBL16003515 | 0.79 | SYK (0.47) | HTTSYKMAPK1AHRSRC | |
| SCHEMBL29497529 | 0.78 | SYK (0.54) | HTTSYKMAPK1EGFRBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104968664-A | BICYCLIC COMPOUND FUNCTIONING AS TYROSINE KINASE INHIBITOR | KBP BIOSCIENCES CO LTD | 2015-10-07 | — | — | CN | disclosed |