SCHEMBL28040000

SCHEMBL28040000

CCCCCCl.O=Cc1ccc[nH]1

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.44
HIF1A Q16665 1/20 0.41
EPAS1 Q99814 1/20 0.41
ALDH1A1 P00352 4/20 0.39
TSHR P16473 2/20 0.39
GPR84 Q9NQS5 2/20 0.33
TDP1 Q9NUW8 3/20 0.32
MAPT P10636 2/20 0.32
RAB9A P51151 2/20 0.32
NPC1 O15118 1/20 0.32
NFKB1 P19838 1/20 0.32
NFKB2 Q00653 1/20 0.32
RELA Q04206 1/20 0.32
ACHE P22303 1/20 0.32
TLK2 Q86UE8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.31
LMNA P02545 1/20 0.31
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Alcohol SCHEMBL28026604 0.78 MAPT (0.41) GAAALDH1A1TSHRMAPTRAB9A
SCHEMBL10141196 0.78
SCHEMBL19596 0.78
Methyl Alcohol SCHEMBL11864407 0.76
Hydrochloric Acid SCHEMBL28194910 0.75
SCHEMBL27449483 0.75
Ether SCHEMBL27635098 0.75 CYP3A4 (0.39) GAAHIF1AEPAS1ALDH1A1MAPT
Butyric Acid SCHEMBL28345734 0.73 TSHR (0.45) GAAALDH1A1TSHRMAPTRAB9A
SCHEMBL27437455 0.69 MAPT (0.46) GAAALDH1A1TSHRTDP1MAPT
Benzene SCHEMBL28236469 0.69 MAPT (0.46) GAAALDH1A1TSHRTDP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105209037-A Lipid furan, pyrrole and thiophene compounds for the treatment of cancer, neurological disorders and fibrotic disorders AVOSCIENCE LLC 2015-12-30 CN disclosed