Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.93 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | MGAM | O43451 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | SI | P14410 | 1/20 | 0.53 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethyl Succinate SCHEMBL7778900 | 1.00 | TSHR (0.93) | TSHRLMNAKDM4EALDH1A1KMT2A | |
| Dimethyl Succinate SCHEMBL28054469 | 0.96 | TSHR (1.00) | TSHRLMNAKDM4EALDH1A1KMT2A | |
| Dimethyl Succinate SCHEMBL10213 | 0.96 | TSHR (1.00) | TSHRLMNAKDM4EALDH1A1KMT2A | |
| Dimethyl Succinate SCHEMBL27773027 | 0.93 | TSHR (0.93) | TSHRLMNAKDM4EALDH1A1KMT2A | |
| Dimethyl Succinate SCHEMBL28108167 | 0.93 | TSHR (0.93) | TSHRLMNAKDM4EALDH1A1KMT2A | |
| Dimethyl Succinate SCHEMBL16798755 | 0.93 | TSHR (0.93) | TSHRLMNAKDM4EALDH1A1KMT2A | |
| Dimethyl Succinate SCHEMBL28294757 | 0.93 | TSHR (0.93) | TSHRLMNAKDM4EALDH1A1KMT2A | |
| Dimethyl Succinate SCHEMBL29248752 | 0.93 | TSHR (0.93) | TSHRLMNAKDM4EALDH1A1KMT2A | |
| Dimethyl Succinate SCHEMBL31389405 | 0.93 | TSHR (0.93) | TSHRLMNAKDM4EALDH1A1KMT2A | |
| Dimethyl Succinate SCHEMBL29824778 | 0.93 | TSHR (0.93) | TSHRLMNAKDM4EALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102712563-B | Sulphur methylsuccinic acid (or its salt), its preparation method and comprise its composition | STEPAN CO. (US) | 2015-11-25 | — | — | CN | disclosed |