Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 4/20 | 0.50 |
| ▸ | AKR1A1 | P14550 | 3/20 | 0.50 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.38 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.31 |
| ▸ | S100A4 | P26447 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1086094 | 0.89 | PDK2 (0.41) | AKR1B1AKR1A1PDK2ALDH1A1S100A4 | |
| SCHEMBL29514438 | 0.89 | PDK2 (0.41) | AKR1B1AKR1A1PDK2ALDH1A1S100A4 | |
| SCHEMBL10018671 | 0.84 | PDK2 (0.38) | AKR1B1AKR1A1PDK2S100A4 | |
| SCHEMBL14508375 | 0.82 | PDK2 (0.37) | AKR1B1AKR1A1PDK2S100A4 | |
| SCHEMBL13327239 | 0.82 | PDK2 (0.39) | AKR1B1AKR1A1PDK2S100A4 | |
| SCHEMBL17050173 | 0.82 | PDK2 (0.39) | AKR1B1AKR1A1PDK2S100A4 | |
| SCHEMBL28842226 | 0.81 | AKR1B1 (0.49) | AKR1B1AKR1A1PDK2AKR1B10ALDH1A1 | |
| SCHEMBL431788 | 0.81 | PDK2 (0.50) | PDK2ALDH1A1MAPT | |
| SCHEMBL29854078 | 0.81 | PDK2 (0.50) | PDK2ALDH1A1MAPT | |
| SCHEMBL28912043 | 0.80 | AKR1B1 (0.54) | AKR1B1AKR1A1PDK2AKR1B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105037167-B | A kind of synthetic method of N, N diaryl 2 bromine 6 naphthylamines and its application | 华南理工大学 | 2017-03-01 | — | — | CN | claimed |
| CN-105037167-A | Synthetic method of N, N-diaryl-2-bromine-6-naphthylamine and application thereof | UNIV SOUTH CHINA TECH | 2015-11-11 | — | — | CN | claimed |
| CN-105037167-B | A kind of synthetic method of N, N diaryl 2 bromine 6 naphthylamines and its application | 华南理工大学 | 2017-03-01 | — | — | CN | disclosed |
| CN-105037167-A | Synthetic method of N, N-diaryl-2-bromine-6-naphthylamine and application thereof | UNIV SOUTH CHINA TECH | 2015-11-11 | — | — | CN | disclosed |