Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.62 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.58 |
| ▸ | PPARG | P37231 | 7/20 | 0.58 |
| ▸ | PPARD | Q03181 | 7/20 | 0.58 |
| ▸ | PPARA | Q07869 | 7/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.58 |
| ▸ | TSHR | P16473 | 4/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | TLR2 | O60603 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | FABP4 | P15090 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.58 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | ESR1 | P03372 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | PDE4A | P27815 | 1/20 | 0.58 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6578407 | 1.00 | APEX1 (0.62) | APEX1GPR84PPARGPPARDPPARA | |
| SCHEMBL7825280 | 1.00 | APEX1 (0.62) | APEX1GPR84PPARGPPARDPPARA | |
| SCHEMBL27371330 | 1.00 | APEX1 (0.62) | APEX1GPR84PPARGPPARDPPARA | |
| SCHEMBL1527397 | 1.00 | APEX1 (0.62) | APEX1GPR84PPARGPPARDPPARA | |
| SCHEMBL8042587 | 1.00 | APEX1 (0.62) | APEX1GPR84PPARGPPARDPPARA | |
| SCHEMBL9635411 | 1.00 | APEX1 (0.62) | APEX1GPR84PPARGPPARDPPARA | |
| SCHEMBL10589927 | 1.00 | APEX1 (0.62) | APEX1GPR84PPARGPPARDPPARA | |
| SCHEMBL9340883 | 1.00 | APEX1 (0.62) | APEX1GPR84PPARGPPARDPPARA | |
| SCHEMBL28041062 | 1.00 | APEX1 (0.62) | APEX1GPR84PPARGPPARDPPARA | |
| Hydrochloric Acid SCHEMBL11404988 | 0.98 | APEX1 (0.60) | APEX1GPR84PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105085636-B | Vancomycin derivatives, preparation method thereof and application thereof in antibiosis | 中国医学科学院药物研究所 | 2020-05-01 | — | — | CN | disclosed |
| CN-105085636-A | Vancomycin derivative, preparation method and antibacterial application thereof | INST MATERIA MEDICA CAMS | 2015-11-25 | — | — | CN | disclosed |