⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL975699 | 0.77 | — | — | |
| SCHEMBL29001079 | 0.75 | — | — | |
| SCHEMBL975333 | 0.75 | — | — | |
| SCHEMBL25397850 | 0.73 | TSHR (0.43) | — | |
| SCHEMBL27906692 | 0.71 | — | — | |
| SCHEMBL2347883 | 0.71 | — | — | |
| SCHEMBL29180900 | 0.71 | — | — | |
| SCHEMBL27714311 | 0.71 | CSNK2A1 (0.38) | — | |
| SCHEMBL16266726 | 0.68 | — | — | |
| Hydrochloric Acid SCHEMBL6186117 | 0.68 | CYP3A4 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117045653-A | Diseases and treatments associated with toxic aldehydes | 奥尔德拉医疗公司 | 2023-11-14 | — | — | CN | disclosed |
| CN-111135171-B | Diseases and treatments associated with toxic aldehydes | 奥尔德拉医疗公司 | 2023-09-08 | — | — | CN | disclosed |
| CN-114085236-A | Aldehyde conjugates and uses thereof | 奥尔德拉医疗公司 | 2022-02-25 | — | — | CN | disclosed |
| CN-111135171-A | Diseases and treatments associated with toxic aldehydes | 奥尔德拉医疗公司 | 2020-05-12 | — | — | CN | disclosed |
| CN-105120866-B | Diseases and treatments associated with toxic aldehydes | 奥尔德拉医疗公司 | 2020-02-14 | — | — | CN | disclosed |
| CN-105120866-A | Diseases and Treatments Associated with Toxic Aldehydes | ALDEYRA THERAPEUTICS INC | 2015-12-02 | — | — | CN | disclosed |