Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 17/20 | 0.56 |
| ▸ | FLT4 | P35916 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | JAK3 | P52333 | 7/20 | 0.52 |
| ▸ | JAK2 | O60674 | 6/20 | 0.50 |
| ▸ | IGF1R | P08069 | 1/20 | 0.49 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10206189 | 0.87 | PTK2 (0.54) | PTK2FLT4KDRJAK3JAK2 | |
| SCHEMBL27933726 | 0.85 | PTK2 (0.54) | PTK2JAK3JAK2IGF1R | |
| SCHEMBL14643618 | 0.85 | PTK2 (0.79) | PTK2FLT4KDR | |
| SCHEMBL14643614 | 0.85 | PTK2 (0.65) | PTK2FLT4KDRJAK3 | |
| SCHEMBL15506716 | 0.84 | PTK2 (0.52) | PTK2FLT4KDRJAK3JAK2 | |
| SCHEMBL14617553 | 0.84 | PTK2 (0.71) | PTK2FLT4KDR | |
| SCHEMBL15506717 | 0.84 | PTK2 (0.49) | PTK2FLT4KDRJAK3JAK2 | |
| SCHEMBL12479392 | 0.84 | PTK2 (0.70) | PTK2FLT4KDR | |
| SCHEMBL12478760 | 0.84 | PTK2 (0.70) | PTK2FLT4KDR | |
| SCHEMBL14577153 | 0.84 | PTK2 (0.82) | PTK2FLT4KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103534241-B | Fak inhibitor | Cancer Therapeutics CRC Pty Ltd. (AU) | 2015-11-25 | — | — | CN | disclosed |