Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | EBP | Q15125 | 1/20 | 0.38 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | SRD5A1 | P18405 | 5/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26917652 | 0.78 | ATM (0.62) | ATMALDH1A1GAAKMT2ASRPK1 | |
| SCHEMBL15664326 | 0.77 | NOTUM (0.51) | NOTUMATMMAPTALDH1A1PARP1 | |
| SCHEMBL15663537 | 0.73 | NOTUM (0.48) | NOTUMATMMAPTALDH1A1SRD5A1 | |
| SCHEMBL1451477 | 0.73 | NOTUM (0.64) | NOTUMXIAPBIRC2USP2LMNA | |
| SCHEMBL27874070 | 0.72 | HRH3 (0.42) | ATMPARP1PARP10HTT | |
| SCHEMBL3530939 | 0.70 | NOTUM (0.44) | NOTUMMAPTALDH1A1KDRSRPK2 | |
| SCHEMBL2481136 | 0.69 | MAPT (0.41) | NOTUMATMMAPTALDH1A1XIAP | |
| SCHEMBL15021599 | 0.69 | ATM (0.42) | NOTUMATMMAPTALDH1A1PARP1 | |
| SCHEMBL14564428 | 0.69 | CHRM2 (0.46) | NOTUMMAPTALDH1A1SRD5A1LMNA | |
| SCHEMBL4692742 | 0.68 | ATM (0.59) | ATMALDH1A1GAAKMT2APSEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104981470-A | Amino-substituted imidazo[1,2-a]pyridinecarboxamides and their use | Bayer Pharma AG | 2015-10-14 | — | — | CN | disclosed |