Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | NQO2 | P16083 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | ACHE | P22303 | 9/20 | 0.60 |
| ▸ | GLA | P06280 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | CASP1 | P29466 | 2/20 | 0.60 |
| ▸ | CASP7 | P55210 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.60 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.60 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15673323 | 0.90 | APP (0.64) | APPKMT2AKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL25757947 | 0.84 | APP (0.74) | APPKMT2AKDM4EMEN1ALDH1A1 | |
| Acridine SCHEMBL28132121 | 0.83 | APP (0.60) | APPKMT2AKDM4EMEN1LMNA | |
| SCHEMBL28572152 | 0.83 | KMT2A (0.74) | KMT2AKDM4ESMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL12488031 | 0.81 | APP (0.70) | APPKMT2AKDM4EMEN1LMNA | |
| SCHEMBL106725 | 0.81 | APP (0.70) | APPKMT2AKDM4EMEN1LMNA | |
| SCHEMBL29365544 | 0.81 | APP (0.70) | APPKMT2AKDM4EMEN1LMNA | |
| SCHEMBL29445571 | 0.81 | APP (0.70) | APPKMT2AKDM4EMEN1LMNA | |
| SCHEMBL13739299 | 0.80 | KMT2A (0.61) | KMT2AKDM4ESMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL31675747 | 0.79 | APP (0.52) | APPKMT2AKDM4ESMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105136787-A | Detection reagent for mono-hydroxyphenyl metabolin urine | SHANGHAI FEI JI BIOTECHNOLOGY CO LTD | 2015-12-09 | — | — | CN | disclosed |