SCHEMBL28042628

SCHEMBL28042628

CCC(C)(CC)Cc1ccccc1O

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 1/20 0.48
IDO1 P14902 2/20 0.45
TSHR P16473 3/20 0.43
CYP2D6 P10635 1/20 0.43
HIF1A Q16665 1/20 0.43
HTR1A P08908 1/20 0.43
TAAR1 Q96RJ0 1/20 0.42
AKR1B1 P15121 1/20 0.42
GABRA1 P14867 1/20 0.41
GABRB2 P47870 1/20 0.41
CA12 O43570 3/20 0.41
CA2 P00918 3/20 0.41
ALDH1A1 P00352 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
CA9 Q16790 2/20 0.39
MPO P05164 1/20 0.39
KEAP1 Q14145 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27980733 0.84 TSHR (0.43) HSPA5IDO1TSHRHTR1A
SCHEMBL10850944 0.83 HSPA5 (0.48) HSPA5IDO1TSHRCYP2D6HIF1A
SCHEMBL27980903 0.83 CNR1 (0.42) TSHRHTR1A
SCHEMBL7172698 0.81 IDO1 (0.52) HSPA5IDO1TSHRCYP2D6HIF1A
SCHEMBL674324 0.80 HSPA5 (0.54) HSPA5IDO1TSHRCYP2D6HIF1A
SCHEMBL15299130 0.80 IDO1 (0.47) HSPA5IDO1TSHRCYP2D6HIF1A
SCHEMBL28092551 0.78 HSPA5 (0.52) HSPA5IDO1TSHRCYP2D6HIF1A
SCHEMBL21483748 0.78 HSPA5 (0.52) HSPA5IDO1TSHRCYP2D6HIF1A
SCHEMBL31607400 0.78 IDO1 (0.48) HSPA5IDO1TSHRCYP2D6HIF1A
SCHEMBL28832424 0.78 IDO1 (0.48) HSPA5IDO1TSHRCYP2D6HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105142605-A 1, 2-alkane polyol-containing composition OSAKA ORGANIC CHEM IND 2015-12-09 CN disclosed