Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | GCGR | P47871 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | RAF1 | P04049 | 1/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27432977 | 0.86 | CNR2 (0.53) | CNR2PDGFRBPDGFRANOS3NOS1 | |
| SCHEMBL28654207 | 0.81 | MAPK14 (0.42) | MAPK14PDGFRBPDGFRAMAPK13MAPK12 | |
| SCHEMBL12970472 | 0.81 | CNR2 (0.49) | CNR2PDGFRBPDGFRANOS3NOS1 | |
| SCHEMBL2479064 | 0.80 | PDE10A (0.48) | CNR2PDGFRBNOS3NOS1NOS2 | |
| SCHEMBL25112013 | 0.79 | CYP1A2 (0.45) | CNR2MAPK14PDGFRBPDGFRAADORA2A | |
| SCHEMBL29038881 | 0.77 | CNR2 (0.45) | CNR2NOS3NOS1NOS2DHODH | |
| SCHEMBL12970125 | 0.77 | MAP2K4 (0.48) | CNR2NOS3NOS1NOS2ABL1 | |
| SCHEMBL21078884 | 0.76 | NPC1 (0.43) | MAPK14ADORA2ALMNADHODH | |
| SCHEMBL24602339 | 0.76 | RPS6KA3 (0.45) | PTGS2DHODH | |
| SCHEMBL17230038 | 0.75 | ALOX5AP (0.40) | MAPK14PDGFRBPDGFRAADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105541640-A | Fluorene derivative, light-emitting element, light-emitting device, electronic device, and lighting device | SEMICONDUCTOR ENERGY LAB | 2016-05-04 | — | — | CN | disclosed |
| CN-102448926-B | Fluorene derivative, light-emitting element, light-emitting device, electronic device, and lighting device | SEMICONDUCTOR ENERGY LABORATORY CO.,LTD. (JP) | 2016-01-20 | — | — | CN | disclosed |